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Lyme disease is caused by the bacterium Borrelia burgdorferi and is to humans through the bite of infected blacklegged ticks. Typical include fever, headache, fatigue, and a characteristic skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system. Lyme disease is based on symptoms, physical findings (e.g., rash), and the possibility of exposure to infected ticks.  Laboratory testing is helpful if used correctly and performed with validated methods. Most cases of Lyme disease can be treated successfully with a few weeks of antibiotics. Steps to Lyme disease include using insect repellent, removing ticks promptly, applying pesticides, and reducing tick habitat. The ticks that transmit Lyme disease can occasionally transmit as well.

  • Image showing blacklegged tick adult female, adult male, nymph, and larva

    Blacklegged (Ixodes scapularis) ticks at all life stages

  • Comic with a boy spraying himself with bug repellent

    Learn more about prevention resources for kids

  • woman holding her temple as if she has a headache

    Lyme Disease Stories

  • Signs and Symptoms of Untreated Lyme Disease

    Signs and symptoms of illness...

  • Treatment

    Lyme disease is treated with antibiotics...

  • Diagnosis and Testing

    Recommended tests...

  • Data and Statistics

    How many people get Lyme disease?

  • Preventing Tick Bites

    Avoid getting infected...

  • Transmission

    How ticks spread Lyme disease...

  • Tick removal and testing

    How to remove a tick...

  • Post-Treatment Lyme Disease Syndrome

    If symptoms persist after treatment...

  • Health Care Providers

    Clinical care information, CME links, and references...

  • Educational Materials

    Brochures, fact sheets, trail signs, and more...

  • Lyme Disease Frequently Asked Questions (FAQ)

    All about Lyme disease...

  • Why is CDC concerned about Lyme disease?

    And what we’re doing to address these concerns…

Helpful Links

  • Video:
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  • Video:

HHS Special Webinars on Lyme and Tickborne Diseases


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